QMSF & SNDDST Woes

First time list poster, but long time lurker! :)

I've configured numerous as/400s for smtp/msf setup using IBM's SNDDST command
but have run into a system thats giving me some trouble. I can verify the jobs
for QMSF and the QMSTP***** are all running but when I run a SNDDST it returns
normally but no mail ever reaches its destination, and one of the QMSF jobs
crashes after each distribution I try to send. I've tried to STRMSF with
*CLEAR, *RESET, *RESUME and nothing seems to help.

I've got my mail logs open on my system and I never even see an initial
connection from the as400. I've checked my TCP/IP routes and everything looks
good, I can ping, telnet, and ftp out of the system, and into the system. The
only oddity I noticed was that the system has two TCP/IP interfaces, one local
and one remote (which the user says he has no idea what it is). The default
route is set to *NONE for the preferred interface, so is it possible its trying
to send out through the 'remote' TCP/IP interface instead of the local one?

Maybe its something simple, which I'm hoping, so if anyone has any ideas it
would be appreciated.

Leonard