SMTP--QMSF job failure

I probably don't have enough information to ask this question intelligently,
but....

A co-worker is trying to get SMTP going and encounters the following error
when calling a program called QSMF:


 Message . . . . :   Integrated File System file open failed on file

   /QTCPTMM/SMTPBOX/Q2697076736.NOTE

 Cause . . . . . :   The RTCP function requires the use of an Integrated
File  
   System file /QTCPTMM/SMTPBOX/Q2697076736.NOTE. The errno return from the

   call is 3025. Either this file is missing, locked or damaged on the
system  
   and cannot be used at this time. Recovery  . . . :   Stop Mail System

   Framework ie. "ENDMSF" and restart "STRMSF". Check earlier entries in Job

   Log for possible reasons for this failure. If system storage problem:
Check 
   Backup and Recovery - Basic, SC41-3304, for the appropriate procedures.

   Likely errno values: EBADNAME    3014  invalid file name specified ENOENT

     3025  No such file or library ENOSPC      3404  No space available EIO

       3006  Input/output error EMFILE      3452  Too many open file handles

   for process EACCES      3401  Permission denied ENOMEM      3460  Storage

   allocation request failed



I've checked and the file doesn't exist.  Don't know what has been done with
the configuration or anything else that might be pertinent.  I'm guessing
that some other process that hasn't run needs to run before QSMF.  

Any ideas at all would be greatly appreciated.  
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